sAPPα相关论文
SCG10 promotes non-amyloidogenic processing of amyloid precursor protein by facilitating its anterog
The processing of amyloid precursor protein (APP) is a key event in the pathogenesis of Alzheimer disease.Certain cleava......
会议
Iron dysregulates APP processing accompanying with sAPPα cellular retention and β-secretase inhibiti
Amyloid precursor protein (APP) and iron both play pivotal roles in the central nervous system,but whether and how iron ......
目的:探讨原花青素对淀粉样蛋白片段Aβ25-35染毒的SH-SY5Y细胞存活、氧化应激及其分泌淀粉样蛋白Aβ1-42和可溶性淀粉样蛋白sAPPα......
淀粉样前体蛋白(APP)的β切割所产生的Aβ阿尔茨海默病(Alzheimer's disease,AD)致病因子。APP的加工方式与特定的亚细胞区域相关,并受......
目的探讨原花青素对淀粉样蛋白片段Aβ 25-35诱导的SH-SY5Y细胞JNK蛋白磷酸化水平及淀粉样蛋白Aβ1-42和可溶性淀粉样蛋白sAPPα分......
三转基因阿尔兹海默症模型小鼠(triple-transgenic Alzheimer’s disease mouse,3×Tg-AD mouse)是目前研究AD病症较为理想的模型......
背景:阿尔兹海默病(Alzheimer’s disease, AD)是一种进行性发展的神经退行性疾病。中医药作为中华民族的传统医学,维系了民族的繁......